ARTHRITIS RHEUMATOID DOCTORS NEAR ME FOR DUMMIES

arthritis rheumatoid doctors near me for Dummies

arthritis rheumatoid doctors near me for Dummies

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Worldwide, many people are suffering from the failure of their immune systems to distinguish between healthy cells and invading microscopic organisms. Their organs and tissue are now being attacked by disease defences which they had previously.




Major international research efforts are in place to combat this trend - for instance, a London-based initiative called the Francis Crick Institute, where two world experts, James Lee and Carola Vinuesa have established separate research groups that will help pinpoint the precise nature of the autoimmune disorder, as these conditions are known.


Lee disclosed to the Observer the extent to which auto-immune cases has grown over the last 40 years in the West. There are now cases in countries that have never had such illnesses before.


For instance, the most recent spike in the number of cases of inflammatory bowel diseases has been located in the Middle East and east Asia. They'd never heard of this disease prior to.


Type 1 diabetes is among the autoimmune diseases. Other ailments include rheumatoid arthritis, inflammation of the bowel, and multiple sclerosis. Each case is different. In all cases, the immune system crosses its wires, and it switches to healthy tissues, not infectious agents.


The UK is home to at least 4,000,000 individuals suffering from these ailments. There are also numerous others. Internationally, it is now estimated that cases of autoimmune diseases are rising between 3% and 9 percent per year. Researchers believe that environmental triggers are key to this rise.


Lee, who was once located in Cambridge University, stated that our genetic makeup has not changed in the last couple of years. There must be a change around the world in a manner that's leading to an increase in our risk of developing the autoimmune disease.


Vinuesa agreed with the idea she was a former employee at the Australian National University. She highlighted changes in the diet occurring as more and more countries adopted western-style diets and people ate more fast food.


Vinuesa noted that fast-food dishes are deficient in certain essential ingredients such as fiber. The evidence suggests that this can alter the microbiome of a person which is the accumulation of microorganisms living in our digestive tract. These microorganisms play a crucial role in controlling many bodily functions.


The changes in our microbiomes can trigger an autoimmune condition, and more than 100 cases have been reported.


Both scientists stressed that individual susceptibilities were involved in contracting diseases like these, which also comprise celiac diseases as well as lupus. Lupus causes swelling and inflammation that can cause damage to various organs, such as the heart.


Vinuesa added, "If there is no genetic susceptibility, then an autoimmune disorder will not always be a concern, regardless of how many Big Macs we consume." "We have no way to slow the growth of fast-food chains across the globe. Therefore we're working to discover the basic genetic mechanisms that underpin the autoimmune diseases that make certain individuals susceptible, while others are not. This is the stage where we plan to tackle this problem."


With the help of modern technology, scientists can now pinpoint small variations in DNA that exist among a large number of people. This is the way it's possible to determine common genetic patterns for patients suffering from an auto immune disease.


Lee said that we did not have the equipment to sequence DNA until recently. In the present, we do have the incredible ability to sequence DNA at huge scales. This has had a profound impact in our lives. We knew only about half a dozen variants of DNA that could cause inflammatory bowel diseases when I started my study. There are now more than 250.


Lee and Vinuesa have been doing such studies since the beginning of. Their efforts aim to unravel the many types of diseases that doctors are currently researching and discover the genetic pathways that lead to them. Vinuesa said that autoimmune diseases such Click here as Lupus, for instance are present in a variety of forms and could have different genetic reasons. That can make it difficult to identify the appropriate treatment.


We are blessed with a wealth of beneficial therapies being developed constantly, but we don't know which patients to give them to, because we've come to realize that we don't know exactly which form of the disease they are suffering from. That's a key goal for the research into autoimmune diseases. For the right treatment, it is necessary to understand how to classify and categorize patients.


Lee stated that the growing incidence of autoimmune diseases around the globe meant that innovative therapies and medications were urgently required. There are currently no treatments for autoimmune disease, which often Read More occur in young people, while they're trying to land their first job, finish school, and raise their families.


This means that more and more of people will have undergo surgery or receive regular injections. This can be very difficult for patients and put an enormous strain on health care systems. We require innovative and effective treatment methods.


Rheumatoid arthritis is an auto-immune condition, which means it's due to the immune system attacking healthy body tissue. It's unclear the reason behind this.


The immune system naturally produces antibodies that fight off viruses and bacteria.


Your immune system might incorrectly release antibodies to your joints if you suffer from Rheumatoid. These antibodies attack the surrounding tissue.


The delicate layer of cells (synovium) that covers your joints, is prone to inflammation and painful.


bones

Cartilage is the connective tissue stretchy that connects bones

Tendons, the tissues that join bone to muscle

Ligaments are the connective tissue that connects bone and cartilage.

If rheumatoid isn't treated, the chemicals slowly cause the joint to loose its shape. These chemicals could eventually cause the destruction of the joint in its entirety.


There are a myriad of theories on the reasons why your immune system attacks joints, which includes the possibility that an infection could be a trigger. However, none of these theories has been proven to be true.


Possible risk factors



There are several things which can increase your chances of developing rheumatoid, for example:


Genetics - Some evidence suggests that rheumatoid joint disease can be passed down through families. However, it is not likely that you'll inherit the condition. Genes are thought to play a small part in the.

hormones - rheumatoid arthritis is more common in females than males, and this could be due to effects of the hormone estrogen, although this link has not been established.

smoking cigarettes - some research suggests that smokers are at a higher risk of developing rheumatoid arthritis.

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